Guide to Filters for RNAi Products

Our filters are key features that empower scientists to quickly focus their search for RNAi reagents from millions of figures and products in our database to help them design better, more successful experiments. 

If there are any types of filters that will help make your search easier and help define your experimental context, please let us know at support@benchsci.com!

How to apply filters

  1. Simply type in search criteria into the search bar alongside your target protein/gene to incorporate them into your search (ex. p53, shRNA)
    • More information about how to build more complex searches in the search bar can be found here!
  2. Click the filter on the left side to add it to your search criteria (you will see it update in the search bar)
    • Some filters include an option to Exclude certain selections (ex. if you want to exclude a particular Selectable Marker)
    • Some filters also include checkboxes to include more than one selection at a time
    • Note: The order in which the filters are presented here may not necessarily reflect how they appear on the platform, as some users may see an alternative recommended filter view

Search logic on the platform

  • During your search, you may want to start combining filters of different types (e.g. Application, Organism Tested...) or multiple instances of the same filter (e.g. Application: Western Blot, Immunohistochemistry)
  • The search logic—that is the use of AND, OR between search terms—on BenchSci aims to be intuitive
    • Search logic is described below under each filter type!

Filter type: Application

  • This filter allows you to narrow down your results based on what type of experiment the product may be used in
    • Based on vendor recommendations or how it has been used in experimental applications in publications
  • Selections include: western blot, immunofluorescence, immunohistochemistry, flow cytometry, knockdown etc.
    • You can also search with common abbreviations/aliases like WB, IF, IHC or flow in the search bar
  • Search logic for multiple selections
    • Product results: AND (all products must have been used with that context for all selections)
    • Figure results: OR (all figure results must contain at least one of the selections)

Filter type: Figure Usage Data

  • These filters help narrow down your search results based on how the product was used in literature
  • Search logic for multiple selections
    • Product results: AND (all products must have been used with that context for all selections)
    • Figure results: OR (all figure results must contain at least one of the selections)

DescriptionExample
Organism Tested
Model or organism in which the experiment was conducted or from which cells or tissues were obtained

This filter also shows a list of aliases/synonyms (ex. homo sapiens will be grouped under human)
Human
Mouse
Drosophila

Tissue Used
Type of tissue that experiments using the product were performed in
Liver
Lung
Cell Type Used
Cell type that experiments using the product were performed in
Epithelial
Neuron
Cell Line Used
Specific names of cell lines that experiments using the product were performed in
HEK293
HeLa cells
Disease
Disease context that experiments using the product were associated with
Breast cancer
Chronic kidney disease

Filter type: Supplier

  • These filters narrow down the results based on information about the vendors themselves
  • Hover over a selection when you open a filter to add Exclude to remove vendors from your search
  • Search logic for multiple selections (Company): OR (the product or figure results need to match at least one of the companies)

Description
Availability
This filter will hide discontinued or unavailable products—the default option is that all products will be shown
Company
The vendor that sells the product. You can choose preferred vendors, or exclude vendors you want to avoid

Filter type: RNAi Specs

  • These filters narrow down the results based on product information that is provided by the vendor
  • Hover over a selection when you open the filter to add Exclude to remove certain results from your search
  • Search logic for multiple selections for both product and figure results
    • AND: Format, Vector, Promoter, Reporter, Selectable Marker, Modification
    • OR: Reactivity, Purification Method

DescriptionExample
RNAi Type
The type of RNAi product
shRNA
siRNA
miRNA
Reactivity
What species the RNAi molecule will target
Human
Mouse
Format
The format that the RNAi reagents come in
Plasmid
Lentiviral particles
Sequence
If you only want to show RNAi products that have a known sequence

Vector
Vehicle to carry the RNAi reagent
piLenti-siRNA-GFP
pZIP-hCMV
Promoter
The promoter in the expression vector (if it comes as a vector) to transcribe the RNAi sequence
CMV promoter
SV40 promoter
Reporter
A detectable molecule attached to the RNAi molecule to help visualize and confirm transfection 
eGFP
mCherry
Selectable Marker
The selectable marker for a plasmid-based RNAi
Puromycin
Zeocin
Modification
Any additional add-ons to the RNAi molecule
Biotin
Fluorescein
Purity
Purity of the RNAi product
> 95%
> 90%
Purification Method
How the RNAi product was purified