Labels for sequence directionality are extracted from the source publication
We trained our machine learning models to read through scientific literature and extract RNAi sequences referenced in figures (see RNAi sequences). Not all scientific publications include a full product citation with vendor and catalog information for RNAi products used in the research, particularly when reagents are developed in-house. The sequences we’ve extracted, although powerful for designing your own oligonucleotides, rely on the sequences as the authors have written them. So, some entries indicate the 5’ and 3’ ends (see image) and others do not.
If you are uncertain about the directionality of the sequence (or you would like to verify it), we recommend clicking out to the original publication to compare to the authors’ notation.