ASCEND has the world’s most powerful and comprehensive biomedical experiment-focused dataset. In addition to our publication corpus, our database is further enriched by a vast library of scientifically trusted third-party sources to surface critical biological/experimental insights and inform our underlying ontological libraries.
We curate and evaluate scientific databases/datasets that provide the most relevant biological data, libraries, and biomedical insights to ASCEND. We leverage these databases through dedicated partnerships and various licensing agreements. We constantly evaluate our databases and underlying libraries to ensure they provide the most value to scientists.
Example datasets that can be directly surfaced as evidence across the platform:
- Online Mendelian Inheritance in Man (OMIM)
- Food and Drug Administration (FDA)
- Mouse Genome Informatics (MGI)
- Human Protein Atlas (HPA)
- UniProt
- Kyoto Encyclopedia of Genes and Genomes (KEGG)
- Retraction Watch
- Clinicaltrials.gov
- dbSNP
Third-party databases that enrich our underlying ontologies, libraries, and scientific insights:
| Database | License Type | Link
| ||
|---|---|---|---|---|
| DrugBank
|
Licensed through a partnership |
N/A | ||
| Kyoto Encyclopedia of Genes and Genomes (KEGG)
|
Licensed through a partnership |
N/A
| ||
| Online Mendelian Inheritance in Man (OMIM)
|
Licensed through a partnership |
N/A | ||
| Small Molecule Pathway Database
|
Licensed through a partnership |
N/A | ||
| miRBase
|
License type: Public Domain |
https://mirbase.org/download/CURRENT/LICENSE/ | ||
|
ENSEMBL |
|
https://useast.ensembl.org/info/about/legal/disclaimer.html | ||
|
|
https://mondo.monarchinitiative.org/#license | ||
|
Entrez |
License type: Public Domain |
https://www.ncbi.nlm.nih.gov/home/about/policies/ | ||
|
Human Phenotype Ontology |
Not a recognized license type, permissive |
|||
|
Gene Ontology |
License type: CC-BY 4.0 |
|||
NCBI Taxonomy | License type: Public Domain | https://www.ncbi.nlm.nih.gov/home/about/policies/ | ||
Therapeutic Target Database | Not a recognized license type, permissive | |||
| License type: Public Domain | https://www.ncbi.nlm.nih.gov/home/about/policies/ | ||
| OrthoDB | License type: CC-BY 4.0 | |||
| Uberon | License type: CC-BY 3.0 | |||
BioGrid | License type: MIT license, copyright 2021 Mike Tyers | |||
| UniProt | License type: CC-BY 4.0 | |||
| STRING | License type: CC-BY 4.0 | https://string-db.org/cgi/accessfooter_active_subpage=licensing | ||
Human Metabolome Database | Licensed through a partnership | N/A | ||
| MarkerDB | Licensed through a partnership | N/A | ||
| Reactome | License type: CC0 | |||
| Human Protein Atlas | License type: CC-BY-SA 4.0 | https://www.proteinatlas.org/about/licence | ||
| BioAssay Ontology | License type: CC-BY 4.0 | |||
Drug Gene Interaction Database (DGIdb) | License type: MIT license | |||
| ChEMBL | License type: CC‑BY‑SA 3.0 | |||
ChEBI | License type: CC-BY 4.0 | https://www.ebi.ac.uk/training/online/courses/chebi-quick-tour/what-is-chebi | ||
dbSNP | License type: Public Domain | https://www.ncbi.nlm.nih.gov/home/about/policies/ | ||
Cell Ontology | License type: CC-BY 4.0 | |||
Cellosaurus | License type: CC-BY 4.0 | |||
Medical Subject Headings (MeSH) | License type: Public Domain | https://www.ncbi.nlm.nih.gov/home/about/policies/ | ||
OpenFDA | License type: CC0 | |||
Drugs@FDA | License type: CC0 | |||
ClinicalTrials.gov | License type: Public Domain | https://www.ncbi.nlm.nih.gov/home/about/policies/. | ||
cBioportal | License type: GNU Affero General Public License v3.0 | https://github.com/cBioPortal/cbioportal/blob/master/LICENSE | ||
Genomic Data Commons | License type: Public Domain | |||
gnomAD | License type: CC0 | |||
| AlphaFold | License type: CC-BY 4.0 | |||
The Cancer Genome Atlas | License type: Public Domain | |||
Genotype-Tissue Expression (GTEx) | License type: Public Domain |